Research - Creatine Vol. 3: Brain Neuro Psych Benefits

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Research - Creatine Vol. 3: Brain Neuro Psych Benefits

Postby Canuck Singh » Fri Jul 18, 2008 7:38 pm

CrM improves Brain Power

Research from the Department of Neuropsychiatry, University of Tokyo has shown that creatine supplementation increases the ability to do calculations and helps you stay alert.

The study involved 19 men and 5 women with an average age of 24. They supplemented with 8 grams of creatine or a placebo for 5 days. They were tested to determine mental fatigue before and after supplementation. Subjects were given numerical calculations to perform for 15 minutes. After a five-minute break another series of calculations were performed for 15 minutes. Near infrared spectroscopy was used to determine changes in brain hemoglobin as a measure of mental fatigue.

The results of the study showed those taking creatine performed substantially better after 5 days of supplementation than at the beginning of the study. Those taking the placebo showed no change.

It appears creatine supplementation increases brain oxygen consumption.

Ref: Neuroscience Research, 2002 April; 42(4):279
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Re: Research - Creatine Vol. 3: Brain Neuro Psych Benefits

Postby Canuck Singh » Tue Aug 19, 2008 5:00 am

Research recently completed by scientists in Australia has shown that the supplement creatine can give a significant boost to both working memory and general intelligence.

This study monitored the effect of creatine supplementation on 45 young adult vegetarian subjects in a double-blind, placebo-controlled experiment. The study was well designed and the effect of creatine supplementation on brain function was quite clear.

In a cross-over design, the scientists gave one group of subject’s creatine (5 grams a day) and a second group a placebo for six weeks; this was followed by a six week period with supplementation and then a final six week trial where the creatine and placebo groups were switched. Intelligence and memory were tested at four points: the start of the trial; the end of the first six week period; and the start and endpoint of the final six week period.

The memory tests involved a backward digit span test - progressively longer verbal random number sequences. Intelligence was tested using Ravens Advanced Progressive Matrices - a methodology commonly used for IQ assessment. These tests were used because they are well validated measures cognitive ability and have minimal dependence on cultural factors. Both of these tests require fast brain power and the Ravens task was conducted under time pressure. The results were clear in both test scenarios; creatine supplementation gave a significant, measurable boost to brain power.

Scientists now realize that creatine plays a pivotal role in maintaining energy levels in the brain. The results of this study confirm previous observations that showed brain creatine levels correlate with improved recognition memory and reduced mental fatigue.

The Australian researcher’s hypothesized that supplementing a diet with creatine would assist brain function and their results proved this to be true! A dose of only 5-grams of creatine a day resulted in improved brain function. If creatine enhances intelligence, I’m going to need to consume a bucket full, everyday!

Proceedings of the Royal Society: Biological Sciences, Vol. 270, No. 1529, (22 October 2003)
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