Fat cells into cartilage?

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Fat cells into cartilage?

Postby Canuck Singh » Wed Oct 01, 2008 10:32 pm

Scientists at Duke University Medical Center have utilized growth factors to transform human fat cells into cartilage cells—research that could be a revelation to millions of people with joint pain.

Growth factors play crucial roles in the differentiation of cells and formation of new tissue. Growth factors are now becoming crucial to the bioengineering of tissue for clinical use in humans. In this study, the Duke team isolated the specialized cells, known as human adipose-derived adult stem cells (hADAS) obtained from body fat during liposuction procedures. The researchers then exposed these fat cells to a cocktail of various growth factors in order to stimulate their transformation into cartilage cells. This research suggests that mixing hADAS cells with certain growth factors could provide tissue that could be used to repair damaged cartilage.

Cartilage is the tissue that provides the cushioning and lubrication of our joints. When cartilage tears it does not heal. Millions of people suffer from arthritis which is the deterioration of cartilage tissue in joints. Therefore, this research has enormous potential benefits for a lot of people. However, if we can develop the technology to be able to turn one type of human cell into another, some potentially exciting and controversial times lay a head in the near future.

Source: The Journal Arthritis and Rheumatism April, 2006.
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Re: Fat cells into cartilage?

Postby Canuck Singh » Thu Oct 09, 2008 3:57 am

People will gladly undergo liposuction to remove excess body fat and improve their looks. However, research has identified that fat contains stem cells with the potential to repair defects and heal injuries in the body. There are hundreds of millions of stem cells in liposuctioned fat that are great at regenerating tissue.

A team led by Philippe Collas at the University of Oslo in Norway has identified certain chemical marks that allow him to predict which, among the hundreds of millions of stem cells in liposuctioned fat, are best at regenerating tissue.

Uncovering the nature and location of these molecular tags could allow scientists to pull off the ultimate trick of taking a patient's own fat cells and using them for therapy.

It appears as though fat tissue is an underappreciated source of stem cells. Best of all, unlike other sources of adult stem cells, such as bone marrow, fat is abundant and there is no shortage of donors. Just imagine, Beverly Hills could become the stem cell research capital of the world, thanks to the millions of liters of liposuctioned “material” that’s obtained from the cosmetic surgery clinics in this area.

Source: EuroSTELLS Workshop 'Exploring Chromatin in Stem Cells' held in Montpellier, France, 2007.
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Re: Fat cells into cartilage?

Postby Domicylla » Thu Sep 20, 2012 12:22 pm

Reduce stress with regular exercise,
Reduce or limit refined carbohydrates and sugar intake,
Avoid caffeine and other stimulants, Limit dairy products and red meat....
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