Coenzyme Q 10 - CoQ10

All about the latest in the supplement world, and all those herbs

Coenzyme Q 10 - CoQ10

Postby Canuck Singh » Wed Aug 27, 2008 10:18 pm

Is Co-Q10 For You?

If you have any concern at all about your memory function, then I want to give you confidence that you can restore your brain cell function and keep it young. The brain is flesh and blood just like the rest of the body.

And recall that because of this one fact alone you can boost your brain power now and prevent memory loss later. Memory loss can be reversed.

One important way to take maximum care of your brain is to use high quality, scientifically proven brain specific nutrients.

Co enzyme Q 10 is one such nutrient.

There is an abundance of recent research that reveals that Co-Q10 is a marvelous addition to your supplement program. Here is an example of some of that research:

As we grow older, our Co-Q10 levels plummet. For example, your heart muscle loses 72% of its coenzyme Q10 during what we call "normal aging."

It's not just limited to your heart either. My own study has shown that Co-Q10 drops like crazy in your brain, too.

That's not good because Co-Q10 is responsible for energy production. Less Co-Q10 means less energy of body and mind.

Moreover, if you take drugs for high cholesterol you must take Co-Q10 because these drugs drain your muscles of this extremely valuable enzyme.

In a very significant and sophisticated research, Co-Q10 was also shown to protect against the neuro-toxic effects of what's called amyloid beta peptides, a very abnormal finding in the brain of Alzheimer's victims.

So, regardless if you're simply concerned about energy and aging or worried about your memory, Co-Q10 is a must.

One more thing. Make sure you don't take anything less than 100mg a day. Why?

That's the absolute best scientifically proven dose for most people. Any less than that simply doesn't work.

It's fine to take more, but don't take less. - Dr Khalsa.
User avatar
Canuck Singh
Site Admin
 
Posts: 1660
Joined: Thu Jun 05, 2008 6:40 pm
Location: Vancouver Canada

Re: Coenzyme Q 10 - CoQ10

Postby Canuck Singh » Mon Oct 27, 2008 8:16 pm

Cellular redox activity of coenzyme Q10: effect of CoQ10 supplementation on human skeletal muscle.
Linnane AW, Kopsidas G, Zhang C, Yarovaya N, Kovalenko S, Papakostopoulos P, Eastwood H, Graves S, Richardson M.

Centre for Molecular Biology and Medicine, Epworth Medical Centre, Richmond, Australia. tlinnane@cmbm.com.au

In this paper, we report results obtained from a continuing clinical trial on the effect of coenzyme Q10 (CoQ10) administration on human vastus lateralis (quadriceps) skeletal muscle. Muscle samples, obtained from aged individuals receiving placebo or CoQ10 supplementation (300mg per day for four weeks prior to hip replacement surgery) were analysed for changes in gene and protein expression and in muscle fibre type composition. Microarray analysis (Affymetrix U95A human oligonucleotide array) using a change in gene expression of 1.8-fold or greater as a cutoff point, demonstrated that a total of 115 genes were differentially expressed in six subject comparisons. In the CoQ10-treated subjects, 47 genes were up-regulated and 68 down-regulated in comparison with placebo-treated subjects. Restriction fragment differential display analysis showed that over 600 fragments were differentially expressed using a 2.0-fold or greater change in expression as a cutoff point. Proteome analysis revealed that, of the high abundance muscle proteins detected (2,086 +/- 115), the expression of 174 proteins was induced by CoQ10 while 77 proteins were repressed by CoQ10 supplementation. Muscle fibre types were also affected by CoQ10 treatment; CoQ10-treated individuals showed a lower proportion of type I (slow twitch) fibres and a higher proportion of type IIb (fast twitch) fibres, compared to age-matched placebo-treated subjects. The data suggests that CoQ10 treatment can act to influence the fibre type composition towards the fibre type profile generally found in younger individuals. Our results led us to the conclusion that coenzyme Q10 is a gene regulator and consequently has wide-ranging effects on over-all tissue metabolism. We develop a comprehensive hypothesis that CoQ10 plays a major role in the determination of membrane potential of many, if not all, sub-cellular membrane systems and that H2O2 arising from the activities of CoQ10 acts as a second messenger for the modulation of gene expression and cellular metabolism.
User avatar
Canuck Singh
Site Admin
 
Posts: 1660
Joined: Thu Jun 05, 2008 6:40 pm
Location: Vancouver Canada

Re: Coenzyme Q 10 - CoQ10

Postby Canuck Singh » Mon Nov 17, 2008 8:54 pm

Coenzyme Q10, also known as ubiquinone, is a dietary supplement with a basis in cardiac research that is now being marketed as a sports ergogenic. It has been studied quite extensively in attempts to examine whether it enhances aerobic power and endurance.

Co-Q10 is involved in several metabolic processes and it is an important part of the oxygen energy (aerobic) system. It is found in the mitochondria of all cells and is an integral part of the electron transport system that generates ATP (energy) via oxidative breakdown of glucose (carbs) and fatty acids.

The research on cardiac patients demonstrated that supplementation with CoQ10 did improve heart function, aerobic capacity and exercise performance. As an antioxidant, taking CoQ10 does show promise. However, so far the peer reviewed, published research on CoQ10 and athletic performance demonstrates quite conclusively that it is ineffective at enhancing any type of aerobic performance.

In fact, one study performed by Swedish researchers* demonstrated that athletes taking 120 milligrams daily for 20 days, exhibited tissue damage compared to those taking a placebo. The authors suspect this may be due to a "pro-oxidant" effect and an increase in free radical damage.

*Malm C, Svensson M, Sjoberg B, et al. Acta Physiologica Scandinavia 157:511-512, 1996.
User avatar
Canuck Singh
Site Admin
 
Posts: 1660
Joined: Thu Jun 05, 2008 6:40 pm
Location: Vancouver Canada
---------


Return to Supplements & Herbs

Who is online

Users browsing this forum: No registered users and 0 guests

cron